Uses |
1. Treatment for Women with metastatic breast cancer recurrence. 2. Used as adjuvant therapy after surgery for breast cancer metastasis, and relapse prevention. 3. For the treatment of ovarian cancer, endometrial cancer and endometriosis. |
Side effects |
1. Early treatment of bone cancer pain and may be a transient increase, continued treatment can be gradually reduced. 2. gastrointestinal reactions: loss of appetite, nausea, vomiting, diarrhea. 3. Reproductive system: menstrual disorders, amenorrhea, vaginal bleeding, genital itching, endometrial hyperplasia, endometrial polyps and endometrial cancer. 4. Skin: facial flushing, rash, hair loss. 5. Bone marrow: occasionally neutropenia and thrombocytopenia. 6. Liver function: occasionally abnormalities. 7. Eyes: using for long time (17 months or more) and large number (240~320mg per day), may appear retinal lesions or corneal opacity . 8. The rare and needed attention of side effects: insanity, pulmonary embolism (showing shortness of breath), thrombosis, weakness, drowsiness. |