What Is Selank Peptide?
Selank is a synthetic peptide derived from tuftsin, another peptide vital for the immune system. As an anxiolytic peptide drug, selank can help patients improve anxiety and depression, learning, memory, and cognition.
But hold on a second!
What is “tuftsin,” and why do scientists synthesize selank based on it?
Tuftsin is an endogenous peptide (a naturally occurring compound in the human body) that also shows anxiolytic effects. The peptide was named after “Tufts University,” where it was first discovered in 1983.
Usually, the amount and concentration of the natural tuftsin in our bodies are minimal. However, when the body is under stress, it releases more tuftsin to settle down the stressor and calm the body.
Unfortunately, the lifespan of tuftsin is very short, no more than several minutes, meaning its effects on our nervous system is transient. To prolong the effects of tuftsin, scientists are working on another synthetic peptide that mimics it but with higher stability.
And here comes the emergence of selank.
What does Selank do for you?
Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species (Kozlovskii and Danchev, 2002; Sollertinskaya et al., 2008; Semenova et al., 2010).
Does Selank really work?
Clinical studies have shown that the anxiolytic effect of Selank is comparable to the effect of low doses of the benzodiazepine tranquilizers; however, the action of Selank is not accompanied by the characteristic side effects of those drugs.
Is Selank natural?
Selank is a synthetic analogue of the immunomodulatory peptide tuftsin; as such, it mimics many of its effects. It has been shown to modulate the expression of Interleukin-6 (IL-6) and affect the balance of T helper cell cytokines.
What is the history of Selank?
Selank is a peptide designed as an analogue of the human body's naturally produced tetrapeptide tuftsin. It was developed in Russia in the early 2000s and since then has been studied extensively for its potential therapeutic properties.
What peptides increase mood?
One peptide called hypocretin has been found to boost mood in humans, which can help ease stress and anxiety. Another peptide, called melanin-concentrating hormone (MHT), increases sleep quality, which can help alleviate the symptoms of various mental health concerns.
The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, ect.
Peptides are shipped at ambient temperature by standard shipment process. Peptides are delivered as lyophilized powders. The apparent volume of powder can be variable between 2 vials containing the same quantity. This difference should not be regarded with suspicion. Some peptides, such as short sequences, are highly hygroscopic and therefore can appear as a gel or can be hardly visible.
Upon receiving the lyophilized peptide, store at 4 °C or colder and away from bright light. Lyophilized peptides are stable at room temperature for weeks, but for longer-term storage, it is safer to store at -20 °C or colder. Exposure to moisture will greatly decrease long-term stability of lyophilized peptides. Before using the peptide, remove from cold storage and allow the peptide to equilibrate to room temperature before removing the lid of the container, in order to reduce the uptake of moisture that is present in the surrounding atmosphere.
The shelf life of peptide solutions is limited. Freezing the aliquots will prolong the storage life of the peptide. What is globally accepted for peptides in solution is that they are generally stable for 2-3 weeks at +4°C and for 3-4 months at -20°C. Avoid repeated freeze-thaw cycles, as this can degrade the peptides.
References
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