Tirzepatide is a once-weekly glucose-dependent insulin-stimulating polypeptide (GIP, aka: gastric inhibitory polypeptide) receptor and glucagon-like peptide-1 (GLP-1) receptor dual agonist developed by Lilly Chemicalbook. Both GIP and GLP-1 are hormones secreted by the gut that promote insulin secretion. tirzepatide combines the effects of two insulin-promoting drugs into a single molecule and represents a new class of drugs for the treatment of type 2 diabetes.
Aliase
|
Tirzepatide;GIP\GLP-1;Tirzepatide (LY3298176) |
CAS |
2023788-19-2 |
EINECS |
200-001-8 |
MOLECULAR FORMULA |
C225H348N48O68 |
MOLECULAR WEIGHT |
4813.45 g/mol |
Medical uses
Tirzepatide has a similar sequence to semaglutide, and the lys side chain in the sequence has PEG modification, which is the functional group of the polypeptide, and can increase the water solubility of the sequence. The main physiological function of TirzepaChemicalbooktide is glucose-dependent insulin nutrition polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor double agonist, which is being developed for the treatment of type 2 diabetes and has entered the clinical stage.
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