Product Description
β-Nicotinamide adenine dinucleotide(NAD+) is used as a coenzyme in redox reactions, as a donor of the ADP ribose moiety in ADP ribosylation reactions, and as a chemicalbook precursor of the second messenger molecule, cyclic ADP ribose. β-nicotinamide adenine dinucleotide also serves as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins, which use NAD+ to remove acetyl groups from proteins.
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Application
NAD+ participates in various physiological activities such as cellular material metabolism, energy synthesis, and cellular DNA repair, and plays an important role in the body's immune ability. In a healthy state, the concentration of NAD+ in the human body is stable to maintain the normal functions of various cells. The NAD+ concentration in the body determines the process and degree of cell aging, and a decrease in the concentration will accelerate the process of cell aging. Studies have shown that NAD+ has a protective effect on renal infarction caused by ischemic surgery, and can significantly reduce blood urea nitrogen and creatinine levels in serum; NAD+ has a protective effect on renal tubular damage caused by ischemic surgery. NAD+ can effectively protect kidney damage caused by renal ischemia, and NAD+ has important application value in the preparation of drugs for preventing and treating renal ischemic damage. In addition, NAD+ has a certain application in the preparation of drugs for the treatment of inflammatory pain. NAD+ participates in the regulation of formalin and complete Freund's adjuvant (CFA)-induced inflammatory pain through NAD+-dependent deacetylases SIRT1 and SIRT2, while SIRT1 and SIRT2 participate in the inhibitory effect of NAD+ on inflammatory pain through different mechanisms, so as to achieve analgesic effect on inflammatory pain.
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Q1: Can you supply the sample?
A1: Yes, we are glad to offer our free samples for your testing.
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A6: Yes, we offer the best price based on your different demands.
Q7: What is your MOQ?
A7: Our MOQ is 1kg, but actually it is negotiable.Q8: How do you ensure its quality?A8: A
ll products are strictly tested by our quality control before shipment, and It has relevant certificate certification.